- Full articles:
- Ioana Teodora Tofolean, Constanta Ganea, Diana
Ionescu, Alexandru Filippi, Alexandru Garaiman,
Alexandru Goicea, Mihnea-Alexandru Gaman, Alexandru
Dimancea, Irina Baran, Cellular determinants
involving mitochondrial dysfunction, oxidative
stress and apoptosis correlate with the synergic
cytotoxicity of epigallocatechin-3-gallate and
menadione in human leukemia Jurkat T cells, PHARMACOLOGICAL
RESEARCH, DOI 10.1016/j.phrs.2015.12.013,
Volume 103, January 2016 pp. 300-317. (if 4,403) (is 1,17)
(ISI) (Q1)
- Irimia Ruxandra, Tofolean Ioana, Ganea Constanta,
Baran Irina, Quercetin, Menadione, Doxorubicin
combination as a potential alternative to
Doxorubicin monotherapy of acute lymphoblastic
leukemia, DOCUMENTA HAEMATOLOGICA, DOI:
10.1515/dch-2015-0005, vol. 34, 1-2, pp. 52-61,
2016, (PubMed,
BDI)
- I. Baran, A. Scordino, D. Ionescu, S. Privitera,
R. Grasso, M. Gulino, F. Musumeci, I.T. Tofolean, C.
Ganea, Functional characterization of mitochondrial
respiratory complex I by delayed luminescence
spectroscopy, LNS ACTIVITY REPORT 2015,
Istituto Nazionale Di Fisica Nucleare Laboratori
Nazionali Del Sud, sub tipar, 2015; Edit. Marchese
Arti Grafiche, Siracusa, Italia; ISSN: 1827-1561 (BDI)
- A. Iftime, C. Ganea, A. Popescu Rightmire,
Interference of coumarin with the insertion of
lyotropic anions and cadmium in artificial lipid
bilayers, ROMANIAN BIOTECHNOLOGICAL LETTERS,
Vol. 20, No. 4, Pages: 10637-10647, 2015 (if.
0.404)(is 0.115) (ISI)
- Agata Scordino, Irina Baran, Marisa Gulino,
Constanta Ganea, Rosaria Grasso, J. Hugo
Niggli,Francesco Musumeci, Ultra-weak Delayed
Luminescence in cancer research: A review of the
results by the ARETUSA equipment, JOURNAL
OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY
139 , pp. 76-84 (2014)(IF 2.803) (is. 0.843)
(ISI)
- Irina Baran, Eva Katona, Constanta Ganea, Quercetin
as a fluorescent probe for the Ryanodine receptor
activity in Jurkat cells, PFLUEGERS
ARCHIV, EUROPEAN JOURNAL OF PHYSIOLOGY,
2013, DOI 10.1007/s00424-013-1235-y, 465 Issue: 8
Pages: 1101-1119. (IF
4.866) (is. 1.857) [link] [link] (ISI)
- Irina Baran, Constanta Ganea, RyR3 in situ
regulation by Ca2+ and quercetin and the
RyR3-mediated Ca2+ release flux in intact Jurkat
cells, ARCHIVES OF BIOCHEMISTRY AND
BIOPHYSICS, 540 (2013) 145–159, [DOI: link], ISSN 0003-9861 [link] (IF. 3.043) (is. 1.285)
(ISI)
- Baran, Irina; Ganea, Constanta; et al., "Detailed
Analysis of Apoptosis and Delayed Luminescence of
Human Leukemia Jurkat T Cells after Proton
Irradiation and Treatments with Oxidant Agents and
Flavonoids", OXIDATIVE MEDICINE AND
CELLULAR LONGEVITY, Article Number:
498914, DOI: 10.1155/2012/498914, 2012 [link] (IF:3.393) (is 0.691)
(ISI)
- Mocanu Maria-Magdalena, Surcel Mihaela, Ursaciuc
Cornel, Katona Eva, Ganea Constanta, Antiproliferative
effect of quercetin in mammary and epidermoid
cancer, ROMANIAN BIOTECHNOLOGICAL
LETTERS, 2013, vol. 18, no. 6, pp.
8796-8803, (IF.
0.363)(is 0.115) [ link ] (ISI)
- Irina Baran, Diana Ionescu, Alexandru Filippi,
Maria Magdalena Mocanu, Adrian Iftime, Ramona Babes,
Ioana Teodora Tofolean, Ruxandra Irimia, Alexandru
Goicea, Valentin Popescu, Alexandru Dimancea, Andrei
Neagu, Constanta Ganea, Novel insights into the
antiproliferative effect of quercetin, menadione
and rotenone in human leukemia Jurkat T cells,
LEUKEMIA RESEARCH, 2014, Volume: 38
Issue: 7 Pages: 836-849, 2014 (IF 2.692) (is. 0.950)
(ISI)
- Irina Baran, Diana Ionescu, Simona Privitera,
Agata Scordino, Maria Magdalena Mocanu, Francesco
Musumeci, Rosaria Grasso, Marisa Gulino, Adrian
Iftime, Ioana Teodora Tofolean, Alexandru Garaiman,
Alexandru Goicea, Ruxandra Irimia, Alexandru
Dimancea, Constanta Ganea, Mitochondrial
respiratory Complex I probed by delayed
luminescence spectroscopy, JOURNAL
OF BIOMEDICAL OPTICS, 2013, 18 (12),
127006, DOI: 10.1117/1.JBO.18.12.127006, (IF 2.752) (is. 1.910)
[ link ] (ISI)
- M.M. Mocanu, C. Ganea, L. Georgescu, T. Varadi, D.
Shrestha, I. Baran, E. Katona, P. Nagy, J.
Szöllösi, Epigallocatechin-gallate
determines ErbB proteins downregulation, cell
death mediated by 67kDa laminin receptor and
altered lipid order in mammary and epidermoid
carcinoma cells, 2013, J. NAT. PROD.,
Volume: 77 Issue: 2, Pages: 250-257, 2014, DOI:
10.1021/np4007712, (IF. 3.947) (is. 2.158)
[ link
] (ISI)
- Agata Scordino, Irina Baran, Marisa Gulino,
Constanta Ganea, Rosaria Grasso, J. Hugo Niggli,
Francesco Musumeci, Ultra-weak Delayed
Luminescence in cancer research: A review of the
results by the ARETUSA equipment, JOURNAL
OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: Biology,
Vol. 139, pp. 76-84, 2014, (IF 2.803) (is. 0.843)
[ link ] (ISI)
- Scientific conferences:
- Baran, I., Katona E., Ganea C., Quercetin
fluorescence reveals the open probability of the
RyR3 Ca2+ channel in intact cells, 22nd IUBMB
Congress/37th FEBS, Seville,
SPAIN, SEP 04-09, 2012, FEBS
JOURNAL Volume: 279
Special Issue: SI Suppl: 1, p: 269-270,
SEP 2011
- Ganea C., Katona E., Baran I., Quercetin
activates the RyR3 receptor in Jurkat human
leukemia cells, invitatie la conferinta
Institutului Max-Planck de Biofizica,
Frankfurt/Main, Germania, 28.10. 2011.
- Agata Scordino, I. Baran, V. Baran, R. Bonfanti,
A. Campisi, C. Ganea, R. Grasso, F. Musumeci, R.
Parenti - New insights into application of
Delayed Luminescence in cancer research - Photodynamic
Therapy and Photodiagnosis in Clinical Practice:
9th International Symposium 2012 (October 16-20,
2012 - Brixen / Bressanone, Italy)
- Ionescu D., Ganea C., Iftime A., Tofolean
I.T., Irimia R., Goicea A., Dimancea A., Neagu A.,
Baran I., Quercetin exerts its antitumoral
effect while manifesting a strong antioxidant
character, 9th European Biophysics Congress -
EBSA 2013, Lisabona, Portugalia
(acceptat), Abstract Booklet, Eur.
Biophys. J., (2013), P52, 42: S35=S208,
S48, 2013
- M.M. Mocanu, P. Nagy, L. Georgescu, T. Varadi, D.
Shrestha, I. Baran, E. Katona, J. Szollosi, C.
Ganea, The effect of flavonoids in mammary and
epidermoid tumor cells with ErbB proteins
overexpression, 8th International
Conference "Structure and Stability of
Biomacromolecules - SSB 2013", 2013,
Kosice, Slovakia
- D. Ionescu, The influence of quercetin on
lipid membranes with cholesterol, 8th
International Conference "Structure and Stability
of Biomacromolecules - SSB 2013", 2013,
Kosice, Slovakia
- Agata Scordino, Irina Baran, Roberta Bonfanti,
Agata Campisi, Costanta Ganea, Rosaria Grasso,
Marisa Gulino, Adrian Iftime, Diana Ionescu, Maria
Magdalena Mocanu, Francesco Musumeci, Rosalba
Parenti - Delayed Luminescence spectroscopy to
monitor mitochondrially targeted effects of cell
proliferation inhibitors - Ultra-weak
Photon Emission From Living Systems Conference
(June 21-23, 2013, Olomouc, Czech Republic) -
Abstract in press on Journal of Acupuncture and
Meridian Studies
- Agata Scordino, I. Baran, R. Bonfanti, A. Campisi,
C. Ganea, R. Grasso, M. Gulino, A. Iftime, D.
Ionescu, M. M. Mocanua, F. Musumeci, R. Parenti - Delayed
Luminescence spectroscopy in cancer research -
XCIX Congresso Nazionale Societa' Italiana
di Fisica (23 - 27 settembre 2013,
Trieste, Italy) – Book of Abstracts p. 120.
- R.G. Sandu, I. Baran, D. Ionescu, A. Filippi, R.
Babes, A. Goicea, A. Garaiman, R. Irimia, A.
Dimancea, M. Gaman, C. Ganea, A. Murgoci. Doxorubicin
induces G2/M arrest, Ca2+ release, oxidative
stress and apoptosis in human leukemia Jurkat
cells at clinical doses and dose rates,
poster (acceptat), FEBS EMBO 2014 Congress,
30 August - 4 Septembrie 2014, Paris, Franta.
Rezumatul va fi publicat în FEBS Journal,
ISSN: 1742-464X; revistă cotată ISI; sub tipar
- M.M. Mocanu, T. Picot, E. Radu, I. Baran, E.
Katona, P. Nagy, J. Szöllősi, L. Campos, C.
Ganea. Modulation of motility and signaling
pathways by epigallocatechin-3-O-gallate in tumor
cell lines overexpressing ErbB proteins,
poster (acceptat), FEBS EMBO 2014 Congress,
30 Aug. - 4 Sept. 2014, Paris, Franta. Rezumatul va
fi publicat în FEBS Journal, ISSN: 1742-464X;
revistă cotată ISI; sub tipar
- Alexandru Garaiman, Diana Ionescu, Alexandru
Filippi, Ramona Babes, Alexandru Goicea, Valentin
Popescu, Ruxandra Irimia, Alexandru Dimancea, Mihnea
Gaman, Adrian Murgoci, Constanta Ganea, Irina Baran.
Synergic antiproliferative effect of
Epigallocatechine-3-gallate and menadione in human
leukemia Jurkat T cells. Poster, 7th
EFIS/EJI South East European Immunology School,
Timişoara, 26-29 sept. 2014
- Mihnea-Alexandru Gaman, Alexandru Filippi, Diana
Ionescu, Constanta Ganea, Irina Baran, Modulation
of the antitumoral effect of doxorubicin by
quercetin-menadione combinations in human leukemia
Jurkat cells, Craiova International
Medical Students Conference (6-9th
November, 2014)
- Valentin Popescu, Bogdan Mastalier, Irina Baran.
Polycaprolactone microspheres loaded with
bioflavonoids and menadione mixture, novel
systemic-friendly approach on cancer. Prezentare
orală acceptată la workshop-ul international
„Electroporation based Technologies and Treatments”
organizat de European Society for Biomaterials,
Ljubljana, Slovenia, 15-21 nov. 2015
- Roxana Gabriela Sandu, Ioana Teodora Tofolean,
Constanta Ganea, Irina Baran. Enhancement of the
antiproliferative effect of doxorubicin by
quercetin-menadione combinations in human leukemia
Jurkat cells. Poster, 6th EMBO (European Molecular
Biology Organization) Meeting, 5-8 sept. 2015,
Birmingham, Marea Britanie
- Alexandru Garaiman, Ioana Teodora Tofolean, Irina
Baran. Chemotherapeutic potential of combination
EGCG:MD in human leukemia Jurkat T cells. Poster,
5th Lower Saxony International Summer Academy in
Immunology, 16 august – 13 september 2015, Hannover
Medical School, Hannover, Germania. Abstract Book
pag. 3
- Oana Elena Baran, Ioana Teodora Tofolean, Ruxandra
Irimia, Irina Baran, Constanta Ganea.
Antiproliferative effect of
doxorubicin/quercetin/menadione combination in
leukemia Jurkat T cells. Poster, 10th EBSA European
Biophysics Congress, 18-22 July 2015, Dresda,
Germania. Late Abstract Booklet p. 44
- Vlad Cosoreanu, Ioana Teodora Tofolean, Constanta
Ganea, Alexandru Goicea, Irina Baran.
Growth-suppressive action of doxorubicin on human
leukemia Jurkat cells. Modulation by quercetin.
Poster, 10th EBSA European Biophysics Congress,
18-22 July 2015, Dresda, Germania. Late Abstract
Booklet p. 45
- Maria Teodora Ilie, Ioana Teodora Tofolean,
Constanta Ganea, Alexandru Dimancea, Irina Baran.
Chemotherapeutic potential of the
doxorubicin/menadione combination in a human
leukemia cell model. Poster, 10th EBSA European
Biophysics Congress, 18-22 July 2015, Dresda,
Germania. Late Abstract Booklet p. 45
- Valentin Popescu, Bogdan Mastalier, Irina Baran.
Bioflavonoids and menadione potential in novel
systemic-friendly approach on cancer. Poster la
workshop-ul international „YOUNG SCIENTISTS JOINING
FORCES FOR EXCELLENCE IN BIOMATERIALS RESEARCH”
organizat de European Society for Biomaterials,
Bucureşti, 28-29 mai 2015. Lucrare distinsă
cu premiul „Best Poster Award”
- Ruxandra Irimia, Irina Baran. Green tea derived
EGCG and vitamin K3: a synergic antiproliferative
effect in acute lymphoblastic leukemia. MEDICALIS
International Congress for Medical Students and
Young Professionals, 14-17 May 2015, Cluj-Napoca
- Paul Ciucur, Simona Costache, Irina Baran,
Constantea Ganea. Possible therapeutic attitude
towards acute lymphoblastic leukemia. MEDICALIS
International Congress for Medical Students and
Young Professionals, 14-17 May 2015, Cluj-Napoca
- Simona Costache, Paul Ciucur, Alexandru Filippi,
Irina Baran. Modularea efectului antitumoral al
doxorubicinei asupra celulelor umane leucemice
Jurkat cu combinații quercetină-menadionă.
Comunicare orală, Congresul Naţional pentru Studenţi
şi Tineri Medici, Bucureşti, martie 2015. Lucrare
distinsă cu Premiul I. Carte de Abstracte
ISSN 2285-9438
- A. Filippi, T. Picot, C.M. Aanei, L. Campos, C.
Ganea, M.M. Mocanu, Epigallocatechin-3-O-gallate
reduces the clonogenicity, induces the mitochondrial
depolarization and increases production of reactive
oxygen species in cancer cell lines with ErbB
proteins overexpression, International Conference of
the Romanian Society of Biochemistry and Molecular
Biology, Bucharest, 17-18 September 2015, ISBN
978-973-720-605-3
- M.M. Mocanu, A. Filippi, T. Picot, C. M. Aanei, L.
Campos, C. Ganea, Anticancer effects of
epigallocatechin-3-O-gallate in tumor cell lines
with ErbB proteins overexpression, poster, National
Conference of Cytometry, May 20, 2015, Bucharest,
Romania
- Oana Elena Baran, Ioana Teodora Tofolean, Maria
Catalina Ceausescu, Constanta Ganea, Analysis of
convergent effects of doxorubicin, quercetin and
menadione in treatments of human leukemia Jurkat T
cells, 12th World Cancer Conference, September
26-28, 2016 London, UK, Abstracts, p. 78, ISSN:
1948-5956
- Vlad Cosoreanu, Ioana Teodora Tofolean, Ramona
Babes, Irina Baran, Cytotoxic effects of doxorubicin
on human leukemia Jurkat T cells. Drug interactions
with quercetin, 12th World Cancer Conference,
September 26-28, 2016 London, UK, Abstracts, p. 79,
ISSN: 1948-5956
- Maria Teodora Ilie, Ioana Teodora Tofolean, Ramona
Babes, Irina Baran, Cytotoxic effect of
doxorubicin/menadione combination on human leukemia
Jurkat cells, 12th World Cancer Conference,
September 26-28, 2016 London, UK, Abstracts, p. 80,
ISSN: 1948-5956
- Oana-Alina Ciolac, Alexandru Filippi, Constanta
Ganea, Maria-Magdalena Mocanu, The effect of
curcumin on epidermoid carcinoma cell line A-431,
Congresul Universitatii de Medicina si Farmacie
Carol Davila, Editia a 4-a, 2-4 iunie 2016,
Bucuresti, Romania
- Alexandru Filippi, Constanta Ganea,
Maria-Magdalena Mocanu, Anti-proliferative effect of
curcumin in ER+ and ErbB2+ mammary cancer cell
lines, Congresul Universitatii de Medicina si
Farmacie Carol Davila, Editia a 4-a, 2-4 iunie 2016,
Bucuresti, Romania
- Alexandru Filippi, Tiphanie Picot, Carmen Mariana
Aanei, Lydia Campos, Constanta Ganea,
Maria-Magdalena Mocanu, EGCG reduces partially the
expression level of intracellular phosphorylated
proteins in correlation with induction of cell death
in epidermoid and mammary cancer cell lines,
Congresul Universitatii de Medicina si Farmacie
Carol Davila, Editia a 4-a, 2-4 iunie 2016,
Bucuresti, Romania
- Awards:
- Key scientific article (Quercetin as a
fluorescent probe for the ryanodine receptor
activity in Jurkat cells, Baran I, Katona E, Ganea
C., Pflugers Arch. 2013 Mar 9.), in Global Medical
Discovery [link]
- Conference Modulation of the antitumoral
effect of doxorubicin by quercetin-menadione
combinations in human leukemia Jurkat cells
received second winning place at Craiova
International Medical Students Conference (6-9th
November, 2014)
- The research articles 1, 2, 5, 6, 7 were awarded
by UEFISCDI
|